Taken from
www.mgcpuzzles.com/mgcpuzzles/artgallery/ Jane_Wooster_Scott/
There is an entirely different process used in making each type of image. A lithograph is a very high quality machine printed image made by using a 4 color separation process much like how the covers of any color magazine is printed.
A Serigraph is a silk screened image. With a Serigraph the original oil painting is scanned and separated digitally into each and every color found in the original. A separate silk screen is created for each and every color that was scanned. There are usually from 80 to 130 individual colors in the majority of some Serigraphs.
Each silk screen is precisely placed over the Serigraph paper, and then by hand squeegee, paint for a specific color is applied. This single application of one paint color must then dry for at least 24 to 48 hours before the next color paint can be applied.
It can take a Serographer up to 6 months to produce 1 run of as many as 500 Serigraphs of the same image.
Serigraphs are also produced in much smaller numbers than Lithographs, and they are as costly to produce, and as close to the actual original painting as you can possibly get.
There is a very noticeable difference in the high quality of a Serigraph (technically original art) when compared to a Lithograph (reproduction).