Muscle glycogen is one of the main energy sources for exercise. In order to be utilized, stored muscle glycogen must be broken down into glucose, a process known as glycolysis. During glycolysis, each glucose molecule is cleaved into two pyruvic acid molecules, and energy is released to form adenosine triphosphate (ATP). Normally, the pyruvic acid enters the mitochondria (the principal cell sites where energy is generated) and undergoes the oxidative stage of glycolysis to produce yet more ATP. However, when there is not enough oxygen present for this reaction to take place, the pyruvic acid transforms into lactic acid. From this point, lactic acid can diffuse out of the muscle cell into the blood. It is by this process (known as anaerobic glycolysis) that muscle glycogen can be converted into energy without the presence of oxygen as opposed to ATP production via aerobic glycolysis. Such a conversion allows glycolysis to proceed for minutes, when it could otherwise last only seconds. Thus, energy is supplied to promote survival in stressful times.
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