No, Sam Walton is not mentioned as an inspiration.
"Earl Hamner's rural childhood, growing up in the unincorporated community of Schuyler, Virginia, provided the basis for many of the story lines of The Waltons."
Also, "He based the cantankerous Walton family grandparents in the popular television series on his own maternal Italian-American grandparents, Ora Lee and A. Gianniny, an anglicized version of the Italian name "Giannini". A recurring character named Connie Giannini (Carla Borelli) appeared on Falcon Crest." https://en.wikipedia.org/wiki/Earl_Hamner
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