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What is the role of the Pacinian corpuscles in human skin?

Question #151409. Asked by psnz.
Last updated Jul 11 2024.
Originally posted Jul 11 2024 8:06 PM.

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BigTriviaDawg star
Answer has 1 vote
BigTriviaDawg star
7 year member
1007 replies avatar

Answer has 1 vote.
Pacinian corpuscles detect any changes in pressure or vibrations on the skin.
Any deformation in the corpuscle leads to opening of pressure-sensitive or stretch-activated ion channels or mechanosensitive channels present in the axon membrane or axolemma of the neurite inside the core of the corpuscles or end-organ. This initiates generation of the receptor potential inside the corpuscles which is also secondarily supported by the voltage-activated ion channels present in the core of the corpuscles. Finally the receptor potential is modulated to neural spikes or action potential with the help of opening of sodium ion channels present at the first Ranvier's Node of the axon.

link https://en.wikipedia.org/wiki/Pacinian_corpuscle

Response last updated by BigTriviaDawg on Jul 11 2024.
Jul 11 2024, 8:08 PM
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