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What does the Meyer-Overton hypothesis try to describe?

Question #150367. Asked by BigTriviaDawg.
Last updated Dec 22 2023.
Originally posted Dec 22 2023 3:36 PM.

psnz

Answer has 1 vote

psnz

5 year member
1007 replies avatar

Answer has 1 vote.

It's all about anaesthetic action, and that its efficacy depends on how well the agent dissolves in lipids.

In 1899 Hans Horst Meyer published the first experimental evidence of the fact that anaesthetic potency is related to lipid solubility. Two years later a similar theory was published independently by Charles Ernest Overton.

https://en.wikipedia.org/wiki/Theories_of_general_anaesthetic_action

Response last updated by psnz on Dec 22 2023.
Dec 22 2023, 3:37 PM

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What does the Meyer-Overton hypothesis try to describe?

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