9. What blood clotting disorder is Queen Victoria blamed for passing on to many of the royal houses in Europe?
From Quiz Queen Victoria's Secret
Answer:
Hemophilia
Hemophilia, or haemophilia, is a genetic blood clotting disorder that usually meant an early death for most of those affected. This is a sex-linked X- chromosome disorder that usually manifests in males. The disorder can be inherited through either parent. For a female to manifest the disease she will have had to inherited the disease from both parents. It is possible that females may have had the disease more often than thought but most would have bled to death upon having their first period. Through her nine children Victoria spread this disease to the royal houses of Spain, Russia and Germany. She, herself, is believed to have carried the trait because of a spontaneous genetic mutation as there was no sign of the disease in her ancestors. The disease became so prevalent in European royalty that it became known as "the kings' disease", "the royal disease" and "Victoria's secret". There are three types of the disease known as A,B, and C. This hereditary disorder impairs the bloods natural ability to clot, varies in severity and death is usually caused by hemorrhage. Today the life expectancy of someone with this disease has risen to 50 years, with proper medication, transfusions, and gene therapy.